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What should I discuss with my healthcare provider before taking anastrozole (Arimidex)?

You should not use this medication if you are allergic to anastrozole, if you are breast-feeding a baby, or if you have not yet completed menopause. Anastrozole is not for use in men or children.

To make sure you can safely take anastrozole, tell your doctor if you have any of these other conditions:

• heart disease;
• circulation problems;
• a history of stroke or blood clot;
• severe liver disease;
• high cholesterol; or
• osteoporosis or low bone mineral density.

Anastrozole can decrease bone mineral density, which may increase your risk of developing osteoporosis. Your bone mineral density may need to be tested before and during treatment with anastrozole.

FDA pregnancy category D. Do not use anastrozole if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether anastrozole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using anastrozole.

You may need to take a pregnancy test before using anastrozole, to make sure you are not pregnant.

How should I take anastrozole (Arimidex)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Anastrozole is usually taken once per day. You may need to keep taking this medication for up to 5 years. Follow your doctor's instructions.

You may take anastrozole with or without food.

Store at room temperature away from moisture and heat.

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