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Medications and Drugs

Brand Names: Iopidine

Generic Name: apraclonidine ophthalmic (Pronunciation: a pra KLAH ni deen)

What is apraclonidine ophthalmic (Iopidine)?

Apraclonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Apraclonidine ophthalmic is used to treat or prevent high pressure inside the eye caused by certain types of eye surgery or procedures.

Apraclonidine ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of apraclonidine ophthalmic (Iopidine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • slow or uneven heart rate;
  • pounding heartbeats or fluttering in your chest;
  • shallow breathing, feeling like you might pass out;
  • severe swelling, redness, or discomfort in or around your eye;
  • eye pain or increased watering; or
  • numbness or tingly feeling in your hands or feet.

Less serious side effects may include:

  • burning, itching, or dryness of your eyes;
  • feeling like something is in your eye;
  • blurred or dimmed vision;
  • redness of the eye or eyelid;
  • mildly swollen or puffy eyes;
  • nausea, stomach pain, diarrhea;
  • headache, sleep problems (insomnia);
  • dry or stuffy nose, burning in your nose;
  • a dry mouth; or
  • unusual or unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about apraclonidine ophthalmic (Iopidine)?

Do not use apraclonidine ophthalmic if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Before using apraclonidine ophthalmic, tell your doctor if you have kidney or liver disease, heart disease, high blood pressure, or a history of fainting or low blood pressure. Also tell your doctor if you are using any medications to treat high blood pressure or a heart rhythm disorder.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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