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Medications and Drugs

Brand Names: Abilify, Abilify Discmelt

Generic Name: aripiprazole (Pronunciation: AR i PIP ra zole)

What is aripiprazole (Abilify, Abilify Discmelt)?

Aripiprazole is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Aripiprazole is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). It is also used together with other medications to treat major depressive disorder in adults.

Aripiprazole is also used to treat irritability and symptoms of aggression, mood swings, temper tantrums, and self-injury related to autistic disorder in children who are at least 6 years old.

Aripiprazole may also be used for purposes not listed in this medication guide.

Abilify 10 mg

rectangular, pink, imprinted with A-008 10

Abilify 15 mg

round, yellow, imprinted with A-009 15

Abilify 20 mg

round, white, imprinted with A-010 20

Abilify 30 mg

round, pink, imprinted with A-011 30

Abilify 5 mg

rectangular, blue, imprinted with A-007 5

What are the possible side effects of aripiprazole (Abilify, Abilify Discmelt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using aripiprazole and call your doctor at once if you have a serious side effect such as:

  • fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
  • jerky muscle movements you cannot control;
  • sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance;
  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • increased thirst or urination, loss of appetite, fruity breath odor, drowsiness, dry skin, nausea, and vomiting;
  • seizure (convulsions);
  • thoughts of hurting yourself;
  • feeling like you might pass out;
  • jaundice (yellowing of your skin or eyes); or
  • urinating less than usual or not at all.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about aripiprazole (Abilify, Abilify Discmelt)?

Aripiprazole is not for use in psychotic conditions that are related to dementia. Aripiprazole may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Stop using aripiprazole and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

Aripiprazole may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid drinking alcohol, which can increase some of the side effects of aripiprazole.

Before you take aripiprazole, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by aripiprazole.

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking aripiprazole.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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