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aspirin and oxycodone (cont.)

What should I discuss with my healthcare provider before taking aspirin and oxycodone (Endodan, Percodan, Roxiprin)?

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.

Do not use aspirin and oxycodone if you have a bleeding or blood clotting disorder such as hemophilia. Do not use this medication if you are allergic to aspirin or oxycodone or to a non-steroidal anti-inflammatory drug (NSAID) such as Advil, Aleve, Motrin, Naprosyn, Orudis, Cataflam, Feldene, Indocin, Lodine, Mobic, Relafen, Toradol, Voltaren, and others.

Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Never share aspirin and oxycodone with another person, especially someone with a history of drug abuse or addiction.

If you have any of these other conditions, you may need a dose adjustment or special tests:

  • asthma or other breathing disorders;
  • liver or kidney disease;
  • a history of head injury or brain tumor;
  • epilepsy or other seizure disorder;
  • stomach or intestinal disorder, history of stomach ulcer or bleeding;
  • a pancreas disorder;
  • curvature of the spine; or
  • mental illness or a history of drug or alcohol addiction.

FDA pregnancy category D. This medication can cause harm to an unborn baby, and breathing problems or addiction/withdrawal symptoms in a newborn. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Do not take aspirin and oxycodone during pregnancy unless your doctor has told you to. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Aspirin and oxycodone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medicine.

How should I take aspirin and oxycodone (Endodan, Percodan, Roxiprin)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking aspirin and oxycodone. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor.

You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

If you need surgery, tell the surgeon ahead of time that you are using aspirin and oxycodone.

Store at room temperature away from moisture, heat, and light.

After you have stopped using this medication, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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