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What should I discuss with my healthcare provider before receiving azacitidine (Vidaza)?
You should not receive this medication if you are allergic to azacitidine or mannitol, or if you have liver cancer.
To make sure you can safely receive azacitidine, tell your doctor if you have any of these other conditions:
FDA pregnancy category D. Do not use azacitidine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Use birth control to prevent pregnancy while you are receiving azacitidine, whether you are a man or a woman. Azacitidine use by either parent may cause birth defects.
If a man fathers a baby while using azacitidine, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 4 weeks after you stop using azacitidine.
It is not known whether azacitidine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using azacitidine.
How is azacitidine given (Vidaza)?
Azacitidine is injected under the skin or into a vein through an IV. You will receive this injection in a clinic or hospital setting.
Azacitidine must be given slowly, and the IV infusion can take up to 40 minutes to complete. If you are receiving a shot under your skin, you may require two injections to complete your dose.
You may also be given medications to reduce nausea and vomiting while you are receiving azacitidine.
This medication is usually given for 7 days in a row every 4 weeks for at least 4 treatment cycles. Your treatment schedule may be different. Follow your doctor's instructions.
Tell your caregiver right away if this medication accidentally gets on your skin. Wash the area thoroughly with soap and warm water.
Azacitidine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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