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What happens if I miss a dose (Azasan, Imuran)?

If you take this medicine once daily and you miss a dose, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

If you take this medicine more than once daily and you miss a dose, take the medicine as soon as you remember. If it is almost time for the next dose, take both doses together, then go back to your regular dosing schedule.

Call your doctor if you have missed more than one dose.

What happens if I overdose (Azasan, Imuran)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach pain, diarrhea, bleeding, fever, chills, and other signs of infection.

What should I avoid while taking azathioprine (Azasan, Imuran)?

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using azathioprine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.

What other drugs will affect azathioprine (Azasan, Imuran)?

Before taking azathioprine, tell your doctor if you are taking, have taken, or need to take any of the following medicines:

• allopurinol (Zyloprim);
• mercaptopurine (Purinethol);
• methotrexate (Rheumatrex, Immunex);
• a blood thinner such as warfarin (Coumadin, Jantoven);
• cyclosporine (Gengraf, Neoral, Sandimmune);
• olsalazine (Dipentum), or sulfasalazine (Azulfidine);
• sulfamethoxasole and trimethoprim (Bactrim, Septra, Sulfatrim, SMX-TMP, others); or
• an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

This list is not complete and other drugs may interact with azathioprine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about azathioprine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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