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May 21, 2012
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Medications and Drugs

Brand Names: Bellamine, Bellamor, Bellaphen-S, Bellaspas, Bellergal-S, Bel-Phen-Ergot, Duragal-S, Eperbel-S, Spastrin

Generic Name: belladonna, ergotamine, and phenobarbital (Pronunciation: bel uh DON uh, er GOT uh meen, and feen oh BAR bit al)

What is belladonna, ergotamine, and phenobarbital (Bellamine, Bellamor, Bellaphen-S, Bellaspas, Bellergal-S, Bel-Phen-Ergot, Duragal-S, Eperbel-S, Spastrin)?

Belladonna is a naturally occurring mixture that produces many effects in the body. It reduces spasms within the stomach and intestines, the bladder, and the biliary (liver) system. Belladonna also reduces the secretions of many organs, which helps control conditions such as excess stomach acid.

Ergotamine narrows the blood vessels involved in circulation to the head. Ergotamine can also alter blood flow patterns involved in vascular headaches, such as migraines.

Phenobarbital is a barbiturate that reduces brain and nervous system activity.

The combination of belladonna, ergotamine, and phenobarbital is used to treat symptoms of menopause including hot flashes, sweating, increased heart rate, dizziness, restlessness, headache, anxiety, and trouble sleeping.

Belladonna, ergotamine, and phenobarbital may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of belladonna, ergotamine, and phenobarbital?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Other less serious side effects are more likely to occur, such as:

  • blurred vision;
  • dry mouth;
  • warmth or tingly feeling;
  • drowsiness; or
  • changes in behavior (in children).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about belladonna, ergotamine, and phenobarbital?

Do not use this medication if you have a history of stroke or blood clots, or if you have glaucoma, heart disease, liver disease, kidney disease, porphyria, or high blood pressure.

This medication can cause birth defects in an unborn baby. Do not use if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

This medication contains phenobarbital, which may be habit-forming. You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using this medication suddenly without first talking to your doctor. You may need to gradually reduce the dose.

Avoid drinking alcohol, which can increase some of the side effects of belladonna, ergotamine, and phenobarbital.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by belladonna, ergotamine, and phenobarbital.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Menopause Overview

Menopause, the time when a woman stops having menstrual periods, is not a disease or an illness. It is a transition between two phases of a woman's life.

Many women experience a variety of symptoms as a result of the hormonal changes associated with the transition through menopause. Around the time of menopause, women often lose bone density and their blood cholesterol levels may worsen, increasing their risk of heart disease.

Premature menopause: The average age of US women at the time of menopause is 51 years. The most common age range at which women experience menopause is 48-55 years. If menopause occurs in a woman younger than 40 years, it is considered to be premature. Menopause is considered late if it occurs in a woman older than 55 years. For most women, menopause is a normal occurrence.

  • Menopause is more likely to occur at a slightly earlier age in women who smoke, have never been pregnant, or live at ...

Read the Menopause article »


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