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Medications and Drugs

Brand Names: Lotrisone

Generic Name: betamethasone and clotrimazole topical (Pronunciation: bay ta METH a sone and kloe TRIM a zole)

What is betamethasone and clotrimazole topical (Lotrisone)?

Clotrimazole is an antifungal antibiotic that treats or prevents infection caused by fungus.

Betamethasone is a topical steroid that reduces itching, swelling, and redness of the skin.

The combination of betamethasone and clotrimazole topical is used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm.

Betamethasone and clotrimazole topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of betamethasone and clotrimazole topical (Lotrisone)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these signs that you may be absorbing betamethasone topical through your skin or gums:

  • swelling, redness, or any signs of new infection;
  • severe burning or stinging of treated skin;
  • weight gain, rounding of the face;
  • increased thirst or hunger, urinating more than usual; or
  • anxiety, depressed mood.

Less serious side effects may include:

  • mild skin itching or irritation;
  • dry skin;
  • changes in skin color;
  • increased acne; or
  • scarring or thinning of the skin.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about betamethasone and clotrimazole topical (Lotrisone)?

Do not cover treated skin areas with a bandage or tight clothing, unless your doctor has told you to.

Do not use this medication on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Never use betamethasone and clotrimazole to treat diaper rash.

It may take up to 1 or 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your groin symptoms do not improve after 1 week, or if your foot symptoms do not improve after 2 weeks of treatment.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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