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bisacodyl and polyethylene glycol (PEG) 3350 with electrolytes (cont.)

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What should I discuss with my health care provider before taking bisacodyl and PEG-3350 (Half Lytely and Bisacodyl Lemon Lime, HalfLytely and Bisacodyl, HalfLytely and Bisacodyl with Flavor Packs)?

Do not use this medication if you are allergic to:

  • bisacodyl (Bisac-Evac, Carter's Little Pills, Dulcolax, Fleet, and others);
  • polyethylene glycol (GlycoLax, MiraLax); or
  • any other electrolyte solutions (such as Pedialyte or Gatorade).

You should not use bisacodyl and PEG-3350 with electrolytes if you have a perforated bowel, a bowel obstruction or severe constipation, or colitis or toxic megacolon. If you have any these conditions, you could have dangerous or life-threatening side effects from bisacodyl and PEG-3350.

People with eating disorders (such as anorexia or bulimia) should not use this medication without the advice of a doctor.

To make sure you can safely use this medication, tell your doctor if you have any of these other conditions:

FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether bisacodyl and PEG-3350 passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child unless your doctor has told you to.

How should I take bisacodyl and PEG-3350 (Half Lytely and Bisacodyl Lemon Lime, HalfLytely and Bisacodyl, HalfLytely and Bisacodyl with Flavor Packs)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

This medicine comes in a kit containing 2 bisacodyl delayed-release tablets and a bottle of PEG-3350 with electrolytes in powder form. You will take the bisacodyl tablets first and then wait to have a bowel movement. Once you have a bowel movement, you will start using the PEG-3350 solution over a period of about 90 minutes.

Bisacodyl delayed-release tablets:

Do not crush, chew, or break the bisacodyl delayed-release tablets. Swallow the tablets whole with a glass of water. Breaking the pill would cause too much of the drug to be released at one time.

You should have a bowel movement within 1 to 6 hours after taking the bisacodyl tablets. After your first bowel movement, start using the PEG-3350 and electrolyte solution.

Polyethylene glycol 3350 and electrolyte solution:

The PEG-3350 and electrolyte powder must be mixed with water before you take it. Fill the container with water up to the 2-liter mark. Place the cap on the bottle and shake it until the powder is completely dissolved.

A variety of flavor packs are provided with the PEG-3350 powder. Use only one pack to add flavor to the solution. You may also prepare the solution without a flavor pack. Do not add any extra flavorings such as sugar, honey, artificial sweetener, fruit juices, or other beverages.

Shake the liquid well just before you measure each dose. The usual dose of PEG-3350 solution is 8 ounces every 10 minutes. Drink the solution in the exact portions at the exact time intervals prescribed by your doctor.

Drink each portion as quickly as possible, rather than sipping it slowly. The first watery stool should appear within 1 hour after you start drinking the PEG-3350 and electrolyte solution.

You may store the mixed solution in a refrigerator but you must use it within 48 hours after mixing. Throw away any PEG-3350 solution you have not used within 48 hours after it was mixed.

PEG-3350 will produce watery diarrhea. Keep drinking the solution until you have consumed all 2 liters.

On the day of your colonoscopy or bowel exam, do not eat solid food or drink anything other than clear liquids. You may be instructed not to drink or eat anything before your medical test or procedure. Follow your doctor's instructions about the type and amount of liquids you should drink for at least 24 hours before and after your test or procedure.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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