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Medications and Drugs

Brand Names: Pylera

Generic Name: bismuth subcitrate potassium, metronidazole, and tetracycline (Pronunciation: BIZ muth sub SIT rate poe TASS ee um, MET roe NYE da zole, TET ra SYE kleen)

What is bismuth subcitrate potassium, metronidazole, and tetracycline (Pylera) (Pylera)?

Bismuth subcitrate potassium is a mineral.

Metronidazole and tetracycline are antibiotics that fight bacteria in the body.

Bismuth subcitrate potassium, metronidazole, and tetracycline (Pylera) is a combination medicine used to treat peptic ulcer (duodenal ulcer) with H pylori infection. Pylera is usually given together with omeprazole (Prilosec).

This medication may also be used for purposes not listed in this medication guide.

What are the possible side effects of Pylera (Pylera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • diarrhea that is watery or bloody;
  • neck stiffness, increased sensitivity to light, purple spots on the skin;
  • seizures (convulsions);
  • severe headache, ringing in your ears, dizziness, vision problems, pain behind your eyes;
  • numbness or tingling in your arms and legs; or
  • signs of an infection such as fever, chills, sore throat, flu symptoms, easy bruising or unusual bleeding, loss of appetite, mouth sores.

Common side effects may include:

  • vaginal itching or discharge;
  • mild diarrhea or other changes in your stools;
  • nausea, upset stomach; or
  • mild headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about bismuth subcitrate potassium, metronidazole, and tetracycline (Pylera) (Pylera)?

Do not use this medicine if you are pregnant or breast-feeding.

Tetracycline can make birth control pills less effective. Ask your doctor about using non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking Pylera.

Do not give this medication to a child younger than 8 years old.

Do not drink alcohol while you are taking Pylera and for at least 1 day after you stop taking it.

Avoid taking Pylera with milk or other dairy products. Also avoid taking the medicine at the same time you take any multivitamins, mineral supplements, or antacids. These products can make it harder for your body to absorb Pylera.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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