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bivalirudin (cont.)

What should I discuss with my health care provider before receiving bivalirudin (Angiomax)?

You should not receive bivalirudin if you are allergic to bivalirudin, or if you have any major bleeding from a surgery, injury, or other medical trauma.

To make sure bivalirudin is safe for you, tell your doctor if you have:

  • heart disease;
  • kidney disease; or
  • a bleeding or blood clotting disorder, such as hemophilia.

FDA pregnancy category B. Bivalirudin is not expected to harm an unborn baby. However, aspirin is usually given with bivalirudin, and aspirin can cause bleeding when it is taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby.

Tell your doctor if you are pregnant before you are treated with bivalirudin and aspirin.

It is not known whether bivalirudin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is bivalirudin given (Angiomax)?

Bivalirudn is injected into a vein through an IV. You will receive this injection during your angioplasty procedure in a clinic or hospital setting. The medicine must be given throughout the entire procedure.

Your doctor may want you to continue receiving bivalirudin for up to 20 hours after your angioplasty procedure.

Bivalirudin is usually given together with aspirin.

Because bivalirudin keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it may be easier for you to bleed even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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