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What should I discuss with my healthcare provider before my child receives botulism immune globulin (BabyBIG)?

Your baby should not receive this medication if he or she has ever had an allergic reaction to an immune globulin, or if the child has immune globulin A (IgA) deficiency with antibody to IgA.

If your baby has certain conditions, he or she may need a dose adjustment or special tests to safely use this medication. Before your baby receives botulism immune globulin, tell your doctor if the baby has:

• kidney disease;
• diabetes;
• a life-threatening infection;
• if the baby is dehydrated; or
• if the baby has recently received any vaccinations.

Botulism immune globulin is made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of treating your child with this medication.

How is botulism immune globulin given (BabyBIG)?

To best participate in the care of your baby while he or she is being treated with botulism immune globulin, carefully follow all instructions provided by your baby's caregivers.

Botulism immune globulin is given as an injection through a needle placed into a vein. Your baby will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take over an hour to complete.

Your baby's breathing, blood pressure, oxygen levels, and other vital signs will be watched closely during treatment with botulism immune globulin.

To be sure this medication is not causing harmful effects, your baby may need blood tests.

Do not miss any follow-up appointments after treatment with botulism immune globulin.

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