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What should I discuss with my healthcare provider before taking bumetanide (Bumex)?

You should not use bumetanide if you are allergic to it, or if you have:

• severe kidney disease or are unable to urinate;
• severe liver disease; or
• if you are severely dehydrated.

If you have any of these other conditions, you may need a dose adjustment or special tests:

• kidney disease;
• liver disease;
• a history of heart rhythm disorder;
• gout;
• diabetes; or
• an allergy to sulfa drugs.

FDA pregnancy category C. It is not known whether bumetanide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether bumetanide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking bumetanide.

How should I take bumetanide (Bumex)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Bumetanide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking bumetanide. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

Store this medication at room temperature away from heat, light, and moisture.

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