buprenorphine (transdermal) (cont.)
What happens if I miss a dose (Butrans)?
If you forget to change a patch on your scheduled day, remove the patch and apply a new one as soon as you remember. Do not wear extra patches to make up a missed dose.
What happens if I overdose (Butrans)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. The amount of buprenorphine in a used or unused skin patch can be fatal to a child who accidentally sucks or chews on the patch.
Overdose symptoms may include extreme drowsiness, weak or limp feeling, weak pulse, cold and clammy skin, fainting, shallow breathing, snoring, or breathing that stops.
What should I avoid while using this drug (Butrans)?
Do not drink alcohol or you may have serious, life-threatening side effects.
This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how buprenorphine will affect you.
Do not expose the skin patch to heat while you are wearing it. This includes a hot tub, heating pad, electric blanket, sauna, heated water bed, or a hot bath. Avoid exposure to sunlight or tanning beds. Heat can increase the amount of drug you absorb through your skin and may cause harmful effects.
Avoid letting another person handle your buprenorphine skin patches. If the sticky side of a skin patch comes into contact with another person, wash the skin with clear water and seek medical care at once.
What other drugs will affect this drug (Butrans)?
Tell your doctor if you regularly use other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicine, sedatives, anti-nausea medicine, other narcotic pain medicines, sleeping pills, muscle relaxers, heart rhythm medications, and medicine for seizures, depression, or anxiety). They can add to the side effects of buprenorphine and dangerous side effects may result.
- dexamethasone (Decadron, Hexadrol);
- St. John's wort;
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- phenobarbital (Solfoton) or other barbiturates;
- diazepam (Valium) or similar medicines such as alprazolam (Xanax), lorazepam (Ativan), clorazepate (Tranxene), and others;
- a heart rhythm medication such as amiodarone (Cordarone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecaininde (Tambocor), procainamide (Pronestyl), propafenone, (Rythmol), quinidine (Quin-G), sotalol (Betapace), and others;
- HIV medication such as efavirenz (Sustiva), etravirine (Intelence), nevirapine (Viramune), or ritonavir (Kaletra, Norvir); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).
This list is not complete and other drugs may interact with buprenorphine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about buprenorphine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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