Medications and Drugs

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Brand Names: Jevtana

Generic Name: cabazitaxel (Pronunciation: ka BAZ i TAX el)

• What is cabazitaxel (Jevtana)?
• What are the possible side effects of cabazitaxel (Jevtana)?
• What is the most important information I should know about cabazitaxel (Jevtana)?
• What should I discuss with my health care provider before receiving cabazitaxel (Jevtana)?
• How is cabazitaxel given (Jevtana)?
• What happens if I miss a dose (Jevtana)?
• What happens if I overdose (Jevtana)?
• What should I avoid while receiving cabazitaxel (Jevtana)?
• What other drugs will affect cabazitaxel (Jevtana)?
• Where can I get more information?

What is cabazitaxel (Jevtana)?

Cabazitaxel is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Cabazitaxel is used together with prednisone to treat prostate cancer that has spread to other parts of the body (metastatic).

Cabazitaxel is usually given after other cancer medicines have been tried without successful treatment.

Cabazitaxel may also be used for purposes not listed in this medication guide.

What are the possible side effects of cabazitaxel (Jevtana)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives, red skin rash; difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• fever, cough, chills, muscle aches, flu symptoms, sores in your mouth and throat, rapid and shallow breathing, fainting;
• pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
• severe or ongoing diarrhea;
• trouble breathing;
• feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
• swelling or rapid weight gain; or
• blood in your urine, pain or burning when you urinate.

Less serious side effects may include:

• nausea, vomiting, stomach pain;
• constipation, mild diarrhea;
• weakness, tired feeling;
• joint pain, back pain;
• numbness, burning pain, or tingly feeling en your hands or feet;
• changes in your sense of taste; or
• hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about cabazitaxel (Jevtana)?

You should not use this medication if you are allergic to cabazitaxel, or if you have liver disease, low white blood cell counts, or an allergy to any medicine that contains polysorbate 80.

You should not breast-feed while you are receiving cabazitaxel.

Before you receive cabazitaxel, tell your doctor if you have ever had a severe allergic reaction to any medication.

Cabazitaxel is used together with prednisone, and you may also be given other medications to help prevent certain side effects. Use all medications as directed by your doctor.

To make sure cabazitaxel is helping your condition and not causing harmful effects, your blood will need to be tested often.

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