caffeine and ergotamine (oral/rectal) (cont.)
What happens if I miss a dose (Cafergot, Migergot)?
Since caffeine and ergotamine is used only when needed, you are not likely to miss a dose.
Do not take more than 6 caffeine and ergotamine tablets per day or more than 10 tablets per week.
Do not use more than 2 suppositories per headache or 5 suppositories per week.
What happens if I overdose (Cafergot, Migergot)?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of caffeine and ergotamine can be fatal.
Overdose can cause vomiting, confusion, drowsiness, weak pulses in your arms and legs, numbness and tingling or pain in your hands or feet, blue-colored fingers or toes, fainting, and seizure (convulsions).
What should I avoid while using caffeine and ergotamine (Cafergot, Migergot)?
Do not use caffeine and ergotamine within 24 hours before or after using another migraine headache medicine, including:
- dihydroergotamine (D.H.E. 45, Migranal), caffeine and ergotamine (Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), methysergide (Sansert); or
- almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), sumatriptan (Imitrex), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig).
Grapefruit and grapefruit juice may interact with caffeine and ergotamine and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
What other drugs will affect caffeine and ergotamine (Cafergot, Migergot)?
Many drugs can interact with caffeine and ergotamine. Below is just a partial list. Talk with your doctor before using caffeine and ergotamine if you are also taking:
- birth control pills;
- zileuton (Zyflo);
- cold or allergy medications;
- nicotine (Nicoderm, Nicorette);
- diet pills, stimulants, or medication to treat ADHD (such as Ritalin or Adderall);
- an antidepressant such fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), nefazodone (Serzone), paroxetine (Paxil), sertraline (Zoloft), and others;
- nitroglycerin or other nitrate medicines such as isosorbide (Isordil, Dilatrate, Imdur, Monoket); or
- heart or blood pressure medication such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.
This list is not complete and there may be other drugs that can interact with caffeine and ergotamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about caffeine and ergotamine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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