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Brand Names: Capoten

Generic Name: captopril (Pronunciation: KAP toe pril)

• What is captopril (Capoten)?
• What are the possible side effects of captopril (Capoten)?
• What is the most important information I should know about captopril (Capoten)?
• What should I discuss with my healthcare provider before taking captopril (Capoten)?
• How should I take captopril (Capoten)?
• What happens if I miss a dose (Capoten)?
• What happens if I overdose (Capoten)?
• What should I avoid while taking captopril (Capoten)?
• What other drugs will affect captopril (Capoten)?
• Where can I get more information?

What is captopril (Capoten)?

Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Captopril is used to treat high blood pressure (hypertension), congestive heart failure, kidney problems caused by diabetes, and to improve survival after a heart attack.

Captopril may also be used for other purposes not listed in this medication guide.

Capoten 100 mg

oval, white, imprinted with CAPOTEN 100

Capoten 12.5 mg-PAR

oblong, white, imprinted with 12.5, CAPOTEN

Captopril 100 mg-APO

oblong, white, imprinted with APO 006

Captopril 100 mg-GG

round, white, imprinted with GG 179

Captopril 100 mg-MYL

round, white, imprinted with M C4

Captopril 100 mg-PAR

round, white, imprinted with E 124

Captopril 100 mg-TEV

oblong, white, imprinted with 100, N 135

Captopril 12.5 mg-APH

round, white, imprinted with AP, 7045

Captopril 12.5 mg-APO

round, white, imprinted with APO 003

Captopril 12.5 mg-MYL

oval, white, imprinted with M C1

Captopril 12.5 mg-TEV

oval, white, imprinted with 93 91

Captopril 25 mg-APO

round, white, imprinted with APO 004

Captopril 25 mg-MYL

round, white, imprinted with M C2

Captopril 25 mg-PAR

round, white, imprinted with E 122

Captopril 25 mg-SCH

round, white, imprinted with INV 272, 25

Captopril 25 mg-TEV

round, white, imprinted with N 133

Captopril 50 mg-APH

round, white, imprinted with AP 7047

Captopril 50 mg-APO

oblong, white, imprinted with APO 005

Captopril 50 mg-MYL

round, white, imprinted with M C3

Captopril 50 mg-TEV

oblong, white, imprinted with 50, N 134

Captropril 25 mg-WAT

round, white, imprinted with 689 25, WATSON

What are the possible side effects of captopril (Capoten)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• feeling light-headed, fainting;
• urinating more or less than usual, or not at all;
• fever, chills, body aches, flu symptoms;
• pale skin, easy bruising or bleeding;
• fast, pounding, or uneven heartbeats;
• chest pain; or
• swelling, rapid weight gain.

Less serious side effects may include:

• cough;
• loss of taste sensation, loss of appetite;
• dizziness, drowsiness, headache;
• sleep problems (insomnia);
• dry mouth, sores in the mouth or on the lips;
• nausea, diarrhea, constipation; or
• mild skin itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about captopril (Capoten)?

Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Captopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of captopril.

Do not use salt substitutes or potassium supplements while taking captopril, unless your doctor has told you to.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking captopril. Drink plenty of water each day while you are taking this medication.

What should I discuss with my healthcare provider before taking captopril (Capoten)?

Do not use this medication if you are allergic to captopril or to any other ACE inhibitor, such as benazepril (Lotensin), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before you take captopril, tell your doctor if you have:

• kidney disease (or if you are on dialysis);
• liver disease;
• heart disease or congestive heart failure;
• diabetes; or
• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Captopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Captopril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take captopril (Capoten)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take each dose with a full glass of water.

Captopril is usually taken 1 hour before meals. Follow your doctor's instructions.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking captopril. Drink plenty of water each day while you are taking this medication.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking captopril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store captopril at room temperature away from moisture and heat.

What happens if I miss a dose (Capoten)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Capoten)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.

What should I avoid while taking captopril (Capoten)?

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of captopril.

Do not use salt substitutes or potassium supplements while taking captopril, unless your doctor has told you to.

What other drugs will affect captopril (Capoten)?

Before taking captopril, tell your doctor if you are taking any of the following drugs:

• gold injections to treat arthritis;
• lithium (Lithobid, Eskalith);
• a potassium supplement such as K-Dur, Klor-Con;
• salt substitutes that contain potassium;
• drugs that can dilate blood vessels, such as alprostadil (Caverject, Edex), nitroglycerin, nitroprusside (Nitropress), nesiritide (Natrecor), minoxidil (Loniten), or isosorbide dinitrate (Imdur, Isordil);
• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others; or
• a diuretic (water pill).

This list is not complete and there may be other drugs that can interact with captopril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about captopril.

Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medication for the condition prescribed.

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