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Medications and Drugs

Brand Names: Allfen C, Allfen CX, Allres-G, BetaVent, Carba-XP, Certuss, exall, Expectuss, Oratuss, Pulmari-GP, Respi-Tann G, Tusso-ZMR, Tusso-ZR, Xpect-AT

Generic Name: carbetapentane and guaifenesin (Pronunciation: kar BET a PEN tane, and gwye FEN e sin)

What is carbetapentane and guaifenesin (Allfen C, Allfen CX, Allres-G, BetaVent, Carba-XP, Certuss, exall, Expectuss, Oratuss, Pulmari-GP, Respi-Tann G, Tusso-ZMR, Tusso-ZR, Xpect-AT)?

Carbetapentane is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen mucus congestion in your chest and throat, making it easier to cough out through your mouth.

The combination of carbetapentane and guaifenesin is used to treat stuffy nose, cough, and chest congestion caused by the common cold or flu.

This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Carbetapentane and guaifenesin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of carbetapentane and guaifenesin?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • confusion, hallucinations, feeling restless or nervous;
  • tremors; or
  • extreme weakness.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about carbetapentane and guaifenesin?

You should not use this medication if you are allergic to carbetapentane or guaifenesin.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before you take this medication, tell your doctor if you have asthma or other breathing problems, heart disease, high blood pressure, glaucoma, diabetes, an enlarged prostate, urination problems, or an overactive thyroid.

Tell your doctor about all other medicines you use.

Carbetapentane and guaifenesin may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not take carbetapentane and guaifenesin for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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