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Medications and Drugs

Brand Names: C-Tanna 12D, Tannate 12D S, Tannihist-12D, Tussi-12D, Tussi-12D S

Generic Name: carbetapentane, phenylephrine, and pyrilamine (Pronunciation: kar BET a PEN tane, FEN il EFF rin, and pir IL a meen)

What is carbetapentane, phenylephrine, and pyrilamine (C-Tanna 12D, Tannate 12D S, Tannihist-12D, Tussi-12D, Tussi-12D S)?

Carbetapentane is a cough suppressant.

Pyrilamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of carbetapentane, phenylephrine, and pyrilamine is used to treat runny or stuffy nose, sinus congestion, and cough caused by allergies, the common cold, or flu.

Carbetapentane, phenylephrine, and pyrilamine may also be used for other purposes not listed in this medication guide.

What are the possible side effects of carbetapentane, phenylephrine, and pyrilamine (C-Tanna 12D, Tannate 12D S, Tannihist-12D, Tussi-12D, Tussi-12D S)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • slow, shallow breathing;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • urinating less than usual or not at all;
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • dizziness, drowsiness, blurred vision;
  • dry mouth, nose, or eyes;
  • nausea, stomach pain, constipation, loss of appetite;
  • warmth, tingling, or redness under your skin;
  • problems with memory or concentration;
  • ringing in your ears;
  • feeling excited or restless; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about carbetapentane, phenylephrine, and pyrilamine (C-Tanna 12D, Tannate 12D S, Tannihist-12D, Tussi-12D, Tussi-12D S)?

Tell your doctor about all your medical conditions before you take this carbetapentane, phenylephrine, and pyrilamine.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Avoid drinking alcohol while you are taking this medication.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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