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Medications and Drugs

Brand Names: Ancef, Kefzol

Generic Name: cefazolin (Pronunciation: sef A zoe lin)

What is cefazolin (Ancef, Kefzol)?

Cefazolin is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.

Cefazolin injection is used to treat many kinds of bacterial infections, including severe or life-threatening forms.

Cefazolin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of cefazolin (Ancef, Kefzol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
  • fever, chills, body aches, flu symptoms;
  • easy bruising or bleeding, unusual weakness;
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
  • seizure (black-out or convulsions).

Less serious side effects may include:

  • pain, swelling, skin rash, or a hard lump where the injection was given;
  • stomach pain, nausea, vomiting, loss of appetite;
  • skin rash or itching;
  • white patches or sores inside your mouth or on your lips; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about cefazolin (Ancef, Kefzol)?

Do not use cefazolin if you have ever had an allergic reaction to another cephalosporin or to a penicillin without first talking to your doctor.

Before using cefazolin, tell your doctor if you are allergic to any drugs (especially penicillins), or if you have kidney disease, liver disease, or a stomach or intestinal disorder such as colitis.

Before using cefazolin, tell your doctor if you are also using probenecid (Benemid).

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefazolin will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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