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Medications and Drugs

Brand Names: All Day Allergy-D, Zyrtec-D

Generic Name: cetirizine and pseudoephedrine (Pronunciation: se TIR i zeen and SOO doe e FED rin)

What is cetirizine and pseudoephedrine (All Day Allergy-D, Zyrtec-D)?

Cetirizine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of cetirizine and pseudoephedrine is used to treat cold or allergy symptoms such as nasal and sinus congestion, sneezing, itching, watery eyes, or runny nose.

Cetirizine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

Zyrtec-D

round, white, imprinted with ZYRTEC D

What are the possible side effects of cetirizine and pseudoephedrine (All Day Allergy-D, Zyrtec-D)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • weakness, tremors (uncontrolled shaking), or sleep problems (insomnia);
  • severe restless feeling, hyperactivity;
  • extreme feeling of fear or confusion;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
  • problems with vision; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dizziness, drowsiness;
  • tired feeling;
  • dry mouth;
  • nausea, stomach pain, constipation;
  • problems with concentration; or
  • ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about cetirizine and pseudoephedrine (All Day Allergy-D, Zyrtec-D)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

You should not use cetirizine and pseudoephedrine if you are allergic to either drug, or if you have narrow-angle glaucoma, severe high blood pressure (hypertension), severe coronary artery disease, if you are unable to urinate, or if you are allergic to hydralazine (Atarax, Vistaril).

Do not use any other over-the-counter cold medication without first asking your doctor or pharmacist. Pseudoephedrine is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of this drug. Read the label of any other medicine you are using to see if it contains pseudoephedrine.

Cetirizine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of cetirizine.

Call your doctor if your symptoms do not improve, if they get worse, or if you also have a fever.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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