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Medications and Drugs

Brand Names: Aquachloral Supprettes

Generic Name: chloral hydrate rectal (Pronunciation: klor al HYE drate)

What is chloral hydrate rectal (Aquachloral Supprettes)?

Chloral hydrate is a hypnotic and a sedative medication that slows the activity of your central nervous system.

Chloral hydrate rectal is used to treat sleep problems (insomnia). It is sometimes given before a surgery to help you relax.

Chloral hydrate rectal may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of chloral hydrate rectal (Aquachloral Supprettes)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • uneven heartbeats;
  • feeling light-headed, fainting;
  • shallow breathing;
  • weakness, lack of coordination; or
  • a red, blistering, peeling skin rash.

Less serious side effects may be more likely to occur, such as:

  • drowsiness, deep sleep;
  • headache, or hangover feeling;
  • nausea, vomiting, indigestion, gas, stomach pain;
  • redness or drooping of your eyelids;
  • excitement or confusion; or
  • mild itching or skin rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about chloral hydrate rectal (Aquachloral Supprettes)?

Do not take chloral hydrate rectal by mouth. It is for use only in your rectum.

Do not use this medication if you have severe kidney or liver disease, or if you are allergic to chloral hydrate or aspirin.

Tell your doctor if you have any type of kidney, heart, or liver disease, or if you are allergic to aspirin. You may not be able to use chloral hydrate rectal, or you may need a dosage adjustment or special tests during treatment.

Try to empty your bowel and bladder just before using the chloral hydrate rectal suppository. To treat insomnia, use this medicine only at bedtime.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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