Medications and Drugs
Brand Names: Notuss-NXD
Generic Name: chlorcyclizine, codeine, and pseudoephedrine (Pronunciation: klor SYE kli zeen, KOE deen, and SOO doe ee FED rin)
What is chlorcyclizine, codeine, and pseudoephedrine (Notuss-NXD)?
Chlorcyclizine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of chlorcyclizine, codeine, and pseudoephedrine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.
Chlorcyclizine, codeine, and pseudoephedrine may also be used for purposes not listed in this medication guide.
What are the possible side effects of chlorcyclizine, codeine, and pseudoephedrine (Notuss-NXD)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking the medication and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about chlorcyclizine, codeine, and pseudoephedrine (Notuss-NXD)?
You should not use this medication if you have severe liver disease, severe constipation, severe colitis or toxic megacolon, if you are unable to urinate, if you have been sick with diarrhea, if you recently drank large amounts of alcohol, or if you have a head injury or brain tumor.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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