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Medications and Drugs

Brand Names: Coldamine, DryMax, Durahist, Histatab, PCM-LA

Generic Name: chlorpheniramine, methscopolamine, and pseudoephedrine (Pronunciation: KLOR fen IR a meen, METH skoe POL a meen, SOO doe ee FED rin)

What is chlorpheniramine, methscopolamine, and pseudoephedrine (Coldamine, DryMax, Durahist, Histatab, PCM-LA)?

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Methscopolamine reduces the secretions of certain organs in the body.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine, methscopolamine, and pseudoephedrine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Chlorpheniramine, methscopolamine, and pseudoephedrine may also be used for purposes not listed in this medication guide.

What are the possible side effects of chlorpheniramine, methscopolamine, and pseudoephedrine (Coldamine, DryMax, Durahist, Histatab, PCM-LA)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • fast or uneven heart rate;
  • pounding heartbeats or fluttering in your chest;
  • mood changes;
  • tremor, seizure (convulsions);
  • double vision;
  • easy bruising or bleeding, unusual weakness;
  • ongoing diarrhea or vomiting;
  • urinating less than usual or not at all;
  • feeling short of breath; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

Less serious side effects may include:

  • decreased sense of taste;
  • dizziness, drowsiness;
  • dry mouth, nose, or throat;
  • sleep problems (insomnia); or
  • nausea, bloating, constipation;
  • blurred vision;
  • feeling nervous or restless.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about chlorpheniramine, methscopolamine, and pseudoephedrine (Coldamine, DryMax, Durahist, Histatab, PCM-LA)?

You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.

Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.

Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Use the pill finder tool on RxList.



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