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What should I discuss with my doctor before taking chlorpropamide (Diabinese)?
Do not use this medication if you are allergic to chlorpropamide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.
To make sure you can safely take chlorpropamide, tell your doctor if you have any of these other conditions:
Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with chlorpropamide.
FDA pregnancy category C. It is not known whether chlorpropamide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Chlorpropamide can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking chlorpropamide.
How should I take chlorpropamide (Diabinese)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Chlorpropamide is usually taken once per day with breakfast. Follow your doctor's instructions.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating. Hypoglycemia can occur if you skip a meal, exercise too long, drink alcohol, or are under stress.
Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection. Be sure your family and close friends know how to help you in an emergency.
Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.
Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.
Ask your doctor how to adjust your chlorpropamide dose if needed. Do not change your medication dose or schedule without your doctor's advice.
Chlorpropamide is only part of a complete program of treatment that may also include diet, exercise, weight control, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
Use chlorpropamide regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Store at room temperature away from moisture, heat, and light.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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