Medications and Drugs
Brand Names: Clolar
Generic Name: clofarabine (Pronunciation: kloe FAR a been)
What is clofarabine (Clolar)?
Clofarabine is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.
Clofarabine is used to treat acute lymphoblastic leukemia (a type of blood cancer) in children and young adults up to 21 years old.
Clofarabine is usually given after other cancer medicines have been tried without successful treatment.
Clofarabine may also be used for purposes not listed in this medication guide.
What are the possible side effects of clofarabine (Clolar)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about clofarabine (Clolar)?
Do not use clofarabine if you are pregnant. It could harm the unborn baby.
If you have liver or kidney disease, you may need a dose adjustment or special tests to safely receive clofarabine.
To be sure this medication is not causing harmful effects, your blood cells, kidney function, and liver function may need to be tested often. Visit your doctor regularly.
Clofarabine can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Avoid being near people who are sick or have infections. Contact your doctor at once if you develop signs of infection.
Clofarabine can harm your liver or kidneys. This effect is increased when you also use other medicines harmful to the liver or kidneys. During your 5-day treatment with clofarabine, you may need to avoid using certain medications, including some over-the-counter medicines. Tell your doctor about all other medicines you use.
Tell your caregivers at once if you have a serious side effect such as rapid breathing and heart rate, trouble breathing, painful swelling, numbness or tingling, feeling like you might pass out, lower back pain, blood in your urine, urinating less than usual, or jaundice (yellowing of the skin or eyes).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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