IN THIS ARTICLE
What should I discuss with my healthcare provider before receiving clofarabine (Clolar)?
If you have liver or kidney disease, you may need a dose adjustment or special tests to safely receive clofarabine.
FDA pregnancy category D. Do not use clofarabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Use birth control to prevent pregnancy while you are receiving clofarabine, whether you are a man or a woman. Clofarabine use by either parent may cause birth defects.
It is not known whether clofarabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving clofarabine.
How is clofarabine given (Clolar)?
Clofarabine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Clofarabine must be given slowly, and the IV infusion can take at least 2 hours to complete.
Clofarabine is usually given daily for 5 days in a row during one or more treatment cycles. Your doctor will determine how many treatment cycles you will receive and how often.
You may receive other medications to help prevent certain side effects of clofarabine.
Clofarabine can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.
To be sure your blood cells do not get too low, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Your kidney or liver function may also need to be tested. Visit your doctor regularly.
Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, pale skin, easy bruising or bleeding (nosebleeds, bleeding gums), purple or red pinpoint spots under your skin, loss of appetite, mouth sores, or unusual weakness.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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