What happens if I miss a dose (Anafranil)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Anafranil)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of clomipramine can be fatal.
Overdose symptoms may include vomiting, fast or uneven heart rate, loss of balance or coordination, extreme drowsiness, fever, severe sweating, stiff muscles, increased or decreased urination, blue lips or fingernails, weak or shallow breathing, fainting, seizure (convulsions) or coma.
What should I avoid while taking clomipramine (Anafranil)?
Avoid drinking alcohol. It can cause dangerous side effects when taken together with clomipramine.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect clomipramine (Anafranil)?
Taking clomipramine with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking clomipramine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Before taking clomipramine, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), sertraline (Zoloft), trazodone (Desyrel, Oleptro), or vilazodone (Viibryd).
Many drugs can interact with clomipramine. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with clomipramine, especially:
- St. John's wort;
- anti-malaria medication;
- a barbiturate such as phenobarbital or secobarbital;
- bladder or urinary medicines such as darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;
- bronchodilators such as ipratropium or tiotropium;
- cold or allergy medicine, stimulants, or ADHD medication;
- cough medicine that contains dextromethorphan (such as Delsym, Robitussin Maximum Strength, Vicks 44);
- heart or blood pressure medication;
- a heart rhythm medication;
- medication to treat an infection caused by fungus;
- medication to treat HIV or AIDS;
- medication to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel disease;
- medication for Parkinson's disease, such as ropinirole (Requip);
- medicine to treat depression or mental illness; or
- thyroid medication (such as Levothroid, Synthroid, PTU, Northyx, Tapazole).
This list is not complete and many other drugs can interact with clomipramine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about clomipramine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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