Medications and Drugs
Brand Names: Clorpres
Generic Name: clonidine and chlorthalidone (Pronunciation: KLOE ni deen and klor THAL i done)
What is clonidine and chlorthalidone (Clorpres)?
Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.
Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
The combination of clonidine and chlorthalidone treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension).
Clonidine and chlorthalidone may also be used for other purposes not listed in this medication guide.
What are the possible side effects of clonidine and chlorthalidone (Clorpres)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about clonidine and chlorthalidone (Clorpres)?
Do not use this medication if you are unable to urinate.
Avoid drinking alcohol, which can increase some of the side effects of clonidine and chlorthalidone.
Do not stop using this medication suddenly without first talking to your doctor. Stopping this medication suddenly can cause nervousness, anxiety, severe high blood pressure, or life-threatening symptoms. You will need to use less and less before you stop the medication completely.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to the side effects of clonidine and chlorthalidone.
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Keep using clonidine and chlorthalidone as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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