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codeine, diphenhydramine, and phenylephrine (cont.)

What should I discuss with my healthcare provider before taking codeine, diphenhydramine, and phenylephrine (Endal CD)?

Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take codeine, diphenhydramine, and phenylephrine:

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. However, it could cause breathing problems or addiction/withdrawal symptoms in a newborn if the mother takes the medicine during late pregnancy. Before you take acetaminophen and codeine, tell your doctor if you are pregnant or plan to become pregnant during treatment.

This medication may pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication if you are breast-feeding a baby.

Codeine may be habit-forming and should be used only by the person it was prescribed for. Codeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Codeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Older adults may be more likely to have side effects from this medication.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. Talk to your doctor before using this medication if you have phenylketonuria (PKU).

How should I take codeine, diphenhydramine, and phenylephrine (Endal CD)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cough or cold medicine is usually taken for only a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

You may take this medication with or without food. Taking it with food or milk may decrease stomach upset.

This medication may cause dry mouth. You may need to suck on ice chips or hard candy to relieve this side effect.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Talk with your doctor if your symptoms do not improve after 7 days of taking this medication. Call your doctor any time if your symptoms get worse or if you also have a fever, headache, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature away from moisture, heat, and freezing.

Keep track of how much of this medicine been used from each new bottle. Codeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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