Medications and Drugs
Brand Names: Ambifed CD, Ambifed CDX, Ambifed-G CD, Ambifed-G CDX, Biotussin DAC, Cheratussin DAC, Codafed, Codahistine Expectorant, Guaiatussin DAC, Guaifen DAC, Halotussin DAC, Lortuss EX, Maxifed CD, Maxifed CDX, Maxifed-G CD, Maxifed-G CDX, Medent C, Mytussin DAC, Nucofed Pediatric Expectorant, Phenhist Expectorant, Phenylhistine Expectorant, Suttar SF, Suttar-2, Tricode GF, Z-Tuss E
Generic Name: codeine, guaifenesin, and pseudoephedrine (Pronunciation: KOE deen, gwye FEN e sin, and soo doe e FED rin)
What is codeine, guaifenesin, and pseudoephedrine (Ambifed CD, Ambifed CDX, Ambifed-G CD, Ambifed-G CDX, Biotussin DAC, Cheratussin DAC, Codafed, Codahistine Expectorant, Guaiatussin DAC, Guaifen DAC, Halotussin DAC, Lortuss EX, Maxifed CD, Maxifed CDX, Maxifed-G CD, Maxifed-G CDX, Medent C, Mytussin DAC, Nucofed Pediatric Expectorant, Phenhist Expectorant, Phenylhistine Expectorant, Suttar SF, Suttar-2, Tricode GF, Z-Tuss E)?
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of codeine, guaifenesin, and pseudoephedrine is used to treat stuffy nose, cough, sinus congestion, and chest congestion caused by allergies, the common cold, or the flu.
Codeine, guaifenesin, and pseudoephedrine may also be used for purposes not listed in this medication guide.
What are the possible side effects of codeine, guaifenesin, and pseudoephedrine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about codeine, guaifenesin, and pseudoephedrine?
You should not use this medicine if you have severe liver disease, inflammatory bowel disease, severe constipation, a blockage in your stomach or intestines, severe colitis or toxic megacolon, if you have a colostomy or ileostomy, if you are unable to urinate, if you have been sick with diarrhea, if you recently drank large amounts of alcohol, or if you have a head injury or brain tumor.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Codeine may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Cold and Flu Resources
- Dealing With Cold Sores
- Allergy Relief: Antihistamines vs. Decongestants
- Is It a Sore Throat, Strep or Tonsillitis?