conjugated estrogens and medroxyprogesterone (cont.)
IN THIS ARTICLE
What should I discuss with my healthcare provider before taking conjugated estrogens and medroxyprogesterone (Premphase, Prempro)?
Do not use this medication if you have:
If you have any of these other conditions, you may need a dose adjustment or special tests:
Conjugated estrogens increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. Taking progestins while using conjugated estrogens may lower this risk. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using conjugated estrogens and medroxyprogesterone.
Long-term conjugated estrogens treatment may increase your risk of stroke or blood clots. Talk with your doctor about your individual risks before using conjugated estrogens long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.
FDA pregnancy category X. This medication can cause birth defects. Do not use conjugated estrogens and medroxyprogesterone if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
Conjugated estrogens and medroxyprogesterone can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. Do not use if you are breast-feeding a baby.
Do not give this medication to anyone under 18 years old without the advice of a doctor.
How should I take conjugated estrogens and medroxyprogesterone (Premphase, Prempro)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
The 28-day Premphase treatment consists of two differently colored pills, 14 of each color. Carefully follow the patient instructions about which pills to take on days 1 through 14 and which pills to take on days 15 through 28.
You may take this medication with or without food. Try to take the medicine at the same time each day.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using conjugated estrogens and medroxyprogesterone.
Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
If you need surgery, tell the surgeon ahead of time that you are using conjugated estrogens and medroxyprogesterone. You may need to stop using the medicine for a short time.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using conjugated estrogens and medroxyprogesterone.
Store at room temperature away from moisture and heat. Keep the medicine container tightly closed.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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