Medications and Drugs
Brand Names: Premarin Vaginal
Generic Name: conjugated estrogens (vaginal) (Pronunciation: KON joo gay ted ES troe jenz)
What are vaginal conjugated estrogens (Premarin Vaginal)?
Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.
Vaginal conjugated estrogens may also be used for purposes not listed in this medication guide.
What are the possible side effects of vaginal conjugated estrogens (Premarin Vaginal)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using vaginal conjugated estrogens and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about vaginal conjugated estrogens (Premarin Vaginal)?
Vaginal conjugated estrogens can harm an unborn baby or cause birth defects. Do not use if you are pregnant.
You should not use this medication if you have any of the following conditions: a history of heart attack, stroke, or blood clot (especially in your lung or your lower body), liver disease, abnormal vaginal bleeding, or a hormone-related cancer such as breast or uterine cancer.
Long-term treatment with conjugated estrogens may increase your risk of breast cancer, heart attack, or stroke. Talk with your doctor about your individual risks before using vaginal conjugated estrogens long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using vaginal conjugated estrogens.
Vaginal conjugated estrogens should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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