IN THIS ARTICLE
- What is cyclosporine (Gengraf, Neoral, Sandimmune)?
- What are the possible side effects of cyclosporine (Gengraf, Neoral, Sandimmune)?
- What is the most important information I should know about cyclosporine (Gengraf, Neoral, Sandimmune)?
- What should I discuss with my health care provider before taking cyclosporine (Gengraf, Neoral, Sandimmune)?
- How should I take cyclosporine (Gengraf, Neoral, Sandimmune)?
- What happens if I miss a dose (Gengraf, Neoral, Sandimmune)?
- What happens if I overdose (Gengraf, Neoral, Sandimmune)?
- What should I avoid while taking cyclosporine (Gengraf, Neoral, Sandimmune)?
- What other drugs will affect cyclosporine (Gengraf, Neoral, Sandimmune)?
- Where can I get more information?
What happens if I miss a dose (Gengraf, Neoral, Sandimmune)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Gengraf, Neoral, Sandimmune)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can cause nausea, vomiting, pain in your upper stomach, loss of appetite, jaundice (yellowing of the skin or eyes), and urinating less than usual or not at all.
What should I avoid while taking cyclosporine (Gengraf, Neoral, Sandimmune)?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Grapefruit and grapefruit juice may interact with cyclosporine and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
Avoid exposure to sunlight or tanning beds. Cyclosporine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Do not receive a "live" vaccine while using cyclosporine. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
What other drugs will affect cyclosporine (Gengraf, Neoral, Sandimmune)?
Cyclosporine can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys. Many other drugs (including some over the counter medicines) can be harmful to the kidneys. You may need dose adjustments or special tests if you have recently used:
- an antibiotic or antifungal medication;
- cancer medication;
- cholesterol-lowering drugs;
- gout medication;
- medicines to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders;
- an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
- other medicines used to prevent organ transplant rejection; or
- stomach acid reducers (Tagamet, Zantac).
Many other drugs can interact with cyclosporine. Below is just a partial list. Tell your doctor about all other medications you are using, especially:
- birth control pills;
- a diuretic (water pill);
- gout medication;
- heart or blood pressure medication;
- HIV or AIDS medication;
- seizure medication;
- steroid medication (oral, nasal, inhaled, or injectable); or
- St. John's wort.
This list is not complete and there are many other drugs that can interact with cyclosporine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about cyclosporine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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