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cyproheptadine (cont.)

What should I discuss with my healthcare provider before taking cyproheptadine (Periactin)?

Do not use cyproheptadine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not use cyproheptadine if you are allergic to it, or if you have:

  • narrow-angle glaucoma;
  • a stomach ulcer or obstruction;
  • an enlarged prostate or urination problems;
  • if you are having an asthma attack; or
  • if you are elderly or have a debilitating disease.

To make sure you can safely take cyproheptadine, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • a history of asthma;
  • high blood pressure;
  • heart disease; or
  • an overactive thyroid.

FDA pregnancy category B. Cyproheptadine is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether cyproheptadine passes into breast milk, but if it does it could harm a nursing baby. Do not use this medication while you are breast-feeding a baby.

How should I take cyproheptadine (Periactin)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cold and allergy medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store at room temperature away from moisture, heat, and light.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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