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Medications and Drugs

Brand Names: Ampyra

Generic Name: dalfampridine (Pronunciation: dal FAM pri deen)

What is dalfampridine (Ampyra)?

Dalfampridine is a potassium channel blocker.

Dalfampridine is used to improve walking in patients with multiple sclerosis (MS).

Dalfampridine may also be used for purposes not listed in this medication guide.

What are the possible side effects of dalfampridine (Ampyra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking dalfampridine and call your doctor at once if you have a serious side effect such as:

  • seizure (convulsions);
  • pain or burning when you urinate;
  • problems with balance;
  • numbness, burning pain, or tingly feeling;
  • relapse or worsening of MS symptoms;

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dalfampridine (Ampyra)?

You should not use dalfampridine if you are allergic to it, or if you have moderate to severe kidney disease, if you have ever had a seizure (convulsions), or if you are also taking another multiple sclerosis drug called Fampridine.

Before you take dalfampridine, tell your doctor if you have kidney disease.

High doses of dalfampridine may increase your risk of seizure. Do not take more than 2 tablets in a 24-hour period. Do not use a tablet that has been broken or crushed. A broken tablet can release too much of the drug at one time.

Stop taking dalfampridine and call your doctor at once if you a seizure, pain or burning when you urinate, problems with your balance, numbness or tingly feeling, or a relapse of your MS symptoms.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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