Medications and Drugs
Brand Names: Prezista
Generic Name: darunavir (Pronunciation: da ROON a veer)
What is darunavir (Prezista)?
Darunavir is a protease (PRO-tee-ayz) inhibitor. Darunavir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Darunavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Darunavir is not a cure for HIV or AIDS.
Darunavir may also be used for purposes not listed in this medication guide.
What are the possible side effects of darunavir (Prezista)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using darunavir and call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about darunavir (Prezista)?
You should not take this medication if you are allergic to darunavir or ritonavir (Norvir, Kaletra), or if you have severe liver disease.
Darunavir must be taken together with another medication called ritonavir (Norvir). Take the medicines together at the same time every day.
Life-threatening side effects may occur if you take darunavir with alfuzosin, cisapride, pimozide, lovastatin, simvastatin, oral midazolam, triazolam, rifampin, sildenafil (Revatio, for treating pulmonary arterial hypertension), St. John's wort, or an ergot medicine such as Ergomar, Ergotrate, Cafergot, D.H.E. 45, Migranal, Methergine, and others.
Many other drugs can interact with darunavir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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