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What should I discuss with my healthcare provider before taking darunavir (Prezista)?
You should not take this medication if you are allergic to darunavir or ritonavir (Norvir, Kaletra), or if you have severe liver disease.
Some drugs can cause life-threatening side effects if you use them while you are taking darunavir. Do not take darunavir with:
To make sure you can safely take darunavir, tell your doctor if you have any of these other conditions:
FDA pregnancy category C. It is not known whether darunavir will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
Your name may need to be listed on an antiviral pregnancy registry when you start using this medication.
Darunavir can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking darunavir.
Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Darunavir and ritonavir should not be given to a child younger than 6 years old.
How should I take darunavir (Prezista)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Darunavir must be taken together with another medication called ritonavir (Norvir). Take the medicines together at the same time every day.
Take the medicine with a full glass (8 ounces) of water or milk.
Darunavir works best if you take it with food.
Swallow the darunavir tablet whole. Do not break or chew.
Use darunavir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To be sure this medication is helping your condition, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Store at room temperature away from moisture and heat.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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