decitabine (injection) (cont.)
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What should I discuss with my health care provider before receiving decitabine (Dacogen)?
To make sure you can safely take decitabine, tell your doctor if you have any of these other conditions:
FDA pregnancy category D. Do not use decitabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 2 months after you stop receiving decitabine.
It is not known whether decitabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving decitabine.
How is decitabine given (Dacogen)?
Decitabine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Decitabine must be given slowly, and the IV infusion can take up to 3 hours to complete.
In most cases, a decitabine injection is given every 8 hours for 3 days. This 3-day treatment is usually repeated every 6 weeks. You will most likely receive at least 4 of these treatments.
You may be given other medications to prevent nausea or vomiting while you are receiving decitabine.
Decitabine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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