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desmopressin (injection) (cont.)

What should I discuss with my healthcare provider before using injectable desmopressin (DDAVP)?

You should not use this medication if you are allergic to desmopressin, or if you have:

  • severe kidney disease; or
  • if you have ever had hyponatremia (low sodium levels in your body).

Before using desmopressin, tell your doctor if you are allergic to any medications, or if you have:

  • heart disease, coronary artery disease;
  • congestive heart failure;
  • kidney disease;
  • cystic fibrosis;
  • high or low blood pressure;
  • an electrolyte imbalance; or
  • a psychologic disorder that causes extreme or unusual thirst.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use desmopressin.

FDA pregnancy category B. This medication is not expected to harm an unborn baby. Do not use desmopressin without telling your doctor if you are pregnant.

It is not known whether desmopressin passes into breast milk, or if it could harm a nursing baby. Do not use desmopressin without telling your doctor if you are breast-feeding a baby.

How is injectable desmopressin given (DDAVP)?

Desmopressin is given as an injection under your skin or through a needle placed into a vein. In some cases, a healthcare provider will give you this injection. In other cases, you may be shown how to use your medicine at home.

Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Do not use the medication if it has changed colors or has any particles in it. Call your doctor for a new prescription.

It is very important to reduce your intake of water and other fluids while you are using desmopressin. Drinking too much water can cause your body to lose sodium, which may lead to a serious, life-threatening electrolyte imbalance.

Fluid restriction is especially important in children and older adults using desmopressin. Follow your doctor's instructions about the type and amount of liquids you should drink.

To be sure this medication is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with desmopressin. Do not miss any scheduled appointments.

If you are treating hemophilia or von Willebrand's disease, call your doctor if your bleeding is not controlled during treatment with desmopressin.

Store this medicine in the refrigerator. Do not freeze.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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