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Medications and Drugs

Brand Names: Dexall, Panatuss DXP, Panatuss Pediatric DXP, Supress A Pediatric, Tussall, Tussall-ER, Y-Cof DM

Generic Name: dexbrompheniramine, dextromethorphan, and phenylephrine (Pronunciation: dex brom feh NEER a meen, dex tro meh THOR fan, and feh nill EFF rin)

What is dexbrompheniramine, dextromethorphan, and phenylephrine (Dexall, Panatuss DXP, Panatuss Pediatric DXP, Supress A Pediatric, Tussall, Tussall-ER, Y-Cof DM)?

Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dexbrompheniramine, dextromethorphan, and phenylephrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dexbrompheniramine, dextromethorphan, and phenylephrine may also be used for purposes not listed in this medication guide.

What are the possible side effects of dexbrompheniramine, dextromethorphan, and phenylephrine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using dexbrompheniramine, dextromethorphan, and phenylephrine and call your doctor at once if you have:

  • fast, slow, or uneven heart rate;
  • severe headache, mood changes, hallucinations;
  • severe dizziness or anxiety, feeling like you might pass out;
  • tremor, seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • fever;
  • little or no urinating;
  • shortness of breath; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).

Other common side effects may include:

  • mild headache;
  • mild dizziness, drowsiness;
  • dry mouth, nose, or throat;
  • nausea, diarrhea, constipation, upset stomach;
  • feeling nervous, restless, or irritable;
  • blurred vision; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dexbrompheniramine, dextromethorphan, and phenylephrine?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.

Do not use cough or cold medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.

Do not use cough or cold medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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