Medications and Drugs
Brand Names: Promethazine with Dextromethorphan, Promethazine with DM
Generic Name: dextromethorphan and promethazine (Pronunciation: dex troe me THOR fan and pro METH a zeen)
What is dextromethorphan and promethazine (Promethazine with Dextromethorphan, Promethazine with DM)?
Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.
Dextromethorphan and promethazine may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of dextromethorphan and promethazine (Promethazine with Dextromethorphan, Promethazine with DM)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using dextromethorphan and promethazine and call your doctor at once if you have any of these serious side effects:
Keep taking dextromethorphan and promethazine and talk with your doctor if you have any of these less serious side effects:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about dextromethorphan (Promethazine with Dextromethorphan, Promethazine with DM)?
Call your doctor immediately if you experience uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.
Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use dextromethorphan and promethazine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan and promethazine before the MAO inhibitor has cleared from your body.
Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Cold and Flu Resources
- Should You Call the Doctor for a Fever?
- Allergy Relief: Antihistamines vs. Decongestants
- Is It a Sore Throat, Strep or Tonsillitis?