Medications and Drugs
Brand Names: Nuedexta
Generic Name: dextromethorphan and quinidine (Pronunciation: DEX troe meth OR fan and KWIN i deen)
What is dextromethorphan and quinidine (Nuedexta)?
The combination of dextromethorphan and quinidine is used to treat involuntary outbursts of crying or laughing in people with certain neurological disorders, including multiple sclerosis and amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease).
Dextromethorphan and quinidine may also be used for purposes not listed in this medication guide.
What are the possible side effects of dextromethorphan and quinidine (Nuedexta)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using dextromethorphan and quinidine and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about dextromethorphan and quinidine (Nuedexta)?
You should not take dextromethorphan and quinidine if you are also taking quinidine (Quin-G), quinine (Qualaquin), or mefloquine (Lariam), or if you have ever had an allergic reaction or serious medical problem caused by taking any of these medications.
You should not use this medication if you are allergic to dextromethorphan or quinidine, or if you have heart failure, a serious heart condition called "AV block" (unless you have a pacemaker), or a history of Long QT syndrome or life-threatening heart rhythm disorder.
Before you take this medication, tell your doctor if you have slow heartbeats or any other type of heart rhythm disorder, an electrolyte imbalance, bladder or bowel obstruction, myasthenia gravis, or a family history of Long QT syndrome.
There are many other drugs that can cause serious or life threatening medical problems if you take them together with dextromethorphan and quinidine. Tell your doctor about all other medicines you use. Do not start a new medication without telling your doctor.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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