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Medications and Drugs

Brand Names: Altarussin CF, Capmist DM, Despec DM, ExeFen-DMX, Maxifed DM, Medent-DMI, Poly-Vent DM, Robitussin Cold and Cough, Robitussin Pediatric Cough and Decongestant, SudaTex-DM, Suda-Tussin DM, Tusnel, Z-Cof 12DM

Generic Name: dextromethorphan, guaifenesin, and pseudoephedrine (Pronunciation: dex troe meth OR fan, gwye FEN e sin, soo doe e FED rin)

What is dextromethorphan, guaifenesin, and pseudoephedrine (Altarussin CF, Capmist DM, Despec DM, ExeFen-DMX, Maxifed DM, Medent-DMI, Poly-Vent DM, Robitussin Cold and Cough, Robitussin Pediatric Cough and Decongestant, SudaTex-DM, Suda-Tussin DM, Tusnel, Z-Cof 12DM)?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dextromethorphan, guaifenesin, and pseudoephedrine is a combination medicine used to treat stuffy nose, sinus congestion, cough, and chest congestion caused by the common cold or flu.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan, guaifenesin, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Pseudovent DM

oblong, white, imprinted with 438, ETHEX

What are the possible side effects of dextromethorphan, guaifenesin, and pseudoephedrine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

Other common side effects may include:

  • dizziness, drowsiness;
  • sleep problems (insomnia);
  • diarrhea; or
  • feeling nervous, restless, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dextromethorphan, guaifenesin, and pseudoephedrine?

You should not use this medicine if you have untreated or uncontrolled diseases such as high blood pressure or coronary artery disease. Do not use if you are allergic to dextromethorphan, guaifenesin, or pseudoephedrine.

Do not use cough or cold medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Ask a doctor or pharmacist before using any other cold, cough, or allergy medicine. Dextromethorphan, guaifenesin, and pseudoephedrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain medicine. Check the label to see if a medicine contains dextromethorphan, guaifenesin, or pseudoephedrine.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.



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