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dextromethorphan, guaifenesin, and pseudoephedrine (cont.)

What should I discuss with my healthcare provider before using dextromethorphan, guaifenesin, and pseudoephedrine?

You should not use this medicine if you have untreated or uncontrolled diseases such as high blood pressure or coronary artery disease. Do not use if you are allergic to dextromethorphan, guaifenesin, or pseudoephedrine.

Do not use cough or cold medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • diabetes;
  • epilepsy or other seizure disorder;
  • pheochromocytoma (an adrenal gland tumor); or
  • cough with mucus, or cough caused by chronic bronchitis.

FDA pregnancy category C. It is not known whether dextromethorphan, guaifenesin, and pseudoephedrine will harm an unborn baby. Do not use this medicine without medical advice if you are pregnant.

Dextromethorphan, guaifenesin, and pseudoephedrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without medical advice if you are breast-feeding a baby.

Artificially sweetened liquid medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

How should I take dextromethorphan, guaifenesin, and pseudoephedrine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold or cough medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Call doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store at room temperature, away from heat, light, and moisture.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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