Medications and Drugs
Brand Names: Proglycem
Generic Name: diazoxide (oral) (Pronunciation: DYE az OX ide)
What is diazoxide (Proglycem)?
Diazoxide given orally raises blood sugar by slowing the release of insulin from the pancreas.
Diazoxide is used to treat low blood sugar (hypoglycemia) related to certain cancers that affect the pancreas and cause it to release too much insulin.
Diazoxide may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of diazoxide (Proglycem)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about oral diazoxide (Proglycem)?
You should not take this medication if you are allergic to diazoxide or diuretics (water pills). Oral diazoxide should not be used to treat occasional hypoglycemia related to diet.
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Your doctor may occasionally change your dose to make sure you get the best results from this medication.
If your blood sugar gets too high (hyperglycemia), you may have symptoms such as increased thirst, loss of appetite, fruity breath odor, increased urination, drowsiness, dry skin, nausea, and vomiting. Tell your doctor right away if you have any of these symptoms.
To be sure this medication is helping your condition and not causing harmful effects, your urine will need to be tested often for the presence of glucose (sugar) or ketones. You may be able to do this testing at home. Call your doctor if you have any abnormal test result.
Your doctor may also want you to have blood or urine tests at regular intervals. Do not miss any scheduled appointments.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are taking diazoxide.
If your condition does not improve after taking diazoxide for 2 to 3 weeks, stop taking the medication and talk to your doctor.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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