Medications and Drugs
Brand Names: Natazia
Generic Name: dienogest and estradiol (Pronunciation: dye EN oh jest and ESS tra DYE ole)
What is dienogest and estradiol (Natazia)?
Dienogest and estradiol is a combination drug that contains female hormones that prevent ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Dienogest and estradiol is used as contraception to prevent pregnancy. Dienogest and estradiol is also used to treat heavy menstrual bleeding that is not caused by any medical condition of the uterus.
Dienogest and estradiol may also be used for purposes not listed in this medication guide.
What are the possible side effects of dienogest and estradiol (Natazia)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using dienogest and estradiol and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about dienogest and estradiol (Natazia)?
Do not use dienogest and estradiol if you are pregnant or if you have recently had a baby.
You should not take dienogest and estradiol if you have any of the following conditions: uncontrolled high blood pressure, heart disease, a blood-clotting disorder, circulation problems, diabetic problems with your eyes or kidneys, unusual vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you smoke and are over 35, or if you have ever had breast or uterine cancer, jaundice caused by birth control pills, a heart attack, a stroke, or a blood clot.
You may need to use back up birth control, such as condoms or a spermicide, when you first start using this medication or if you miss a dose. Follow your doctor's instructions.
Missing a pill increases your risk of becoming pregnant. Carefully follow the "missed dose" instructions if you forget to take your medicine.
Some drugs can make dienogest and estradiol less effective in preventing pregnancy, including antibiotics, hepatitis C medications, HIV/AIDS medications, seizure medications, or barbiturate sedatives. Tell your doctor about all other medications you use.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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