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diosmiplex, hydrocortisone, and pramoxine (cont.)

What should I discuss with my healthcare provider before taking diosmiplex, hydrocortisone, and pramoxine (Analpram Advanced)?

You should not use this medication if you are allergic to diosmiplex, hydrocortisone, or pramoxine.

To make sure you can safely use this medication, tell your doctor if you have any of these other conditions:

  • liver disease;
  • kidney disease; or
  • if you have ever had cancer.

Also tell your doctor if you have diabetes. Steroid medicines may increase the glucose (sugar) levels in your blood or urine. You may also need to adjust the dose of your diabetes medications.

FDA pregnancy category C. It is not known whether diosmiplex, hydrocortisone, and pramoxine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of topical hydrocortisone.

How should I use diosmiplex, hydrocortisone, and pramoxine (Analpram Advanced)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after applying this medication.

Before you apply the rectal cream, clean the rectal area with a cleansing wipe provided with the Analpram Advanced kit. Follow the directions on the label.

Use only a small amount of medicine when applying the hydrocortisone and pramoxine cream around the outside of the rectum. You may apply the cream 3 to 4 times daily or as directed by your doctor.

Do not cover the treated rectal area with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the area that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Do not use diosmiplex, hydrocortisone, and pramoxine for any condition that has not been checked by a doctor.

Contact your doctor if your condition does not improve or if it gets worse after using this medication.

Store at room temperature away from moisture, heat, and light.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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