What happens if I miss a dose (Adriamycin)?
Call your doctor for instructions if you miss an appointment for your doxorubicin injection.
What happens if I overdose (Adriamycin)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
What should I avoid while taking doxorubicin (Adriamycin)?
Do not receive a "live" vaccine while using doxorubicin, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
What other drugs will affect doxorubicin (Adriamycin)?
Many drugs can interact with doxorubicin. Below is just a partial list. Tell your doctor if you are using:
- acetaminophen (Tylenol);
- an antibiotic or antifungal medication;
- auranofin (Ridaura) or gold injections to treat arthritis;
- cyclosporine (Gengraf, Neoral, Sandimmune);
- dexrazoxane (Totect, Zinecard);
- progesterone (Prometrium);
- rosiglitazone (Avandia, Avandamet, Avandaryl);
- an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), nortriptyline (Pamelor), and others;
- birth control pills or hormone replacement therapy;
- cholesterol medications such as atorvastatin (Lipitor, Caduet), simvastatin (Zocor, Simcor, Vytorin), and others;
- drugs that weaken your immune system, such as adalimumab (Humira), certolizumab (Cimzia), clozapine (Clozaril, FazaClo), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), and others;
- heart rhythm or blood pressure medicine such as amiodarone (Cordarone, Pacerone), benazepril (Lotensin), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), enalapril (Vasotec), labetalol (Normodyne, Trandate), lisinopril (Prinivil, Zestril), methyldopa (Aldomet), quinapril (Accupril), ramipril (Altace), verapamil (Calan, Covera, Isoptin, Verelan, Tarka), and others;
- HIV/AIDS medications;
- non-steroidal anti-inflammatory drugs (NSAIDs) such as (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
- other cancer medications, especially cyclophosphamide Cytoxan, Cytoxan Lyophilized, Neosar), cytarabine (Cytosar, DepoCyt, Tarabine), etoposide (Etopophos, VePesid), paclitaxel (Taxol, Onxol), sorafenib (Nexavar); or
- seizure medications such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), divalproex (Depakote), phenobarbital (Solfoton), phenytoin (Dilantin), valproic acid (Depakene, Stavzor).
This list is not complete and there may be other drugs that can interact with doxorubicin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about doxorubicin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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