Brand Names: Adoxa, Alodox, Avidoxy, Doryx, Monodox, Oracea, Oraxyl, Periostat, Vibra-Tabs, Vibramycin, Vibramycin Calcium, Vibramycin Monohydrate

Generic Name: doxycycline (Pronunciation: DOX i SYE kleen)

• What is doxycycline (Adoxa, Alodox, Avidoxy, Doryx, Monodox, Oracea, Oraxyl, Periostat, Vibra-Tabs, Vibramycin, Vibramycin Calcium, Vibramycin Monohydrate)?
• What are the possible side effects of doxycycline?
• What is the most important information I should know about doxycycline?
• What should I discuss with my healthcare provider before taking doxycycline?
• How should I take doxycycline?
• What happens if I miss a dose?
• What happens if I overdose?
• What should I avoid while taking doxycycline?
• What other drugs will affect doxycycline?
• Where can I get more information?

What is doxycycline (Adoxa, Alodox, Avidoxy, Doryx, Monodox, Oracea, Oraxyl, Periostat, Vibra-Tabs, Vibramycin, Vibramycin Calcium, Vibramycin Monohydrate)?

Doxycycline is a tetracycline antibiotic. It fights bacteria in the body.

Doxycycline is used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, and chlamydia, periodontitis (gum disease), and others.

Doxycycline is also used to treat blemishes, bumps, and acne-like lesions by rosacea. Doxycycline will not treat facial redness caused by rosacea.

Doxycycline may also be used for other purposes not listed in this medication guide.

Adoxa 100 mg

round, yellow, imprinted with B, 729

Adoxa 50 mg

round, yellow, imprinted with 728, B

Adoxa 75 mg

round, orange, imprinted with B, 730

Doryx 100 mg

oval, white/yellow specks, imprinted with D100

Doryx 75 mg

oval, white/yellow specks, imprinted with D75

Doxycycline 100 mg Cap-IVA

turquoise, imprinted with Z 2985

Doxycycline 100 mg Cap-VER

turquoise, imprinted with Westward, 3142

Doxycycline 100 mg Tab-IVA

round, peach, imprinted with Z 3626

Doxycycline 100 mg-EON

brown, imprinted with E810

Doxycycline 100 mg-MUT

turquoise, imprinted with AP 0814

Doxycycline 20 mg-IVA

round, white, imprinted with Logo 20, 4626

Doxycycline 50 mg Cap-IVA

turquoise/white, imprinted with Z 2984, Z2984

Doxycycline 50 mg-EON

yellow, imprinted with E805

Doxycycline 50 mg-MUT

turquoise/white, imprinted with AP 0837

Doxycycline Hyclate 100 mg Tab-URL

round, peach, imprinted with MP 37

Doxycycline Hyclate 100 mg tab-WAT

round, orange, imprinted with 5553, DAN

Doxycycline Hyclate 100 mg-WAT

turquoise, imprinted with DAN 5440

Doxycycline Hyclate 50 mg-WAT

turquoise/white, imprinted with DAN 5535

Doxycycline Monohydrate 100 mg-WAT

brown/yellow, imprinted with 100 mg, WATSON 411

Doxycycline Monohydrate 50 mg-WAT

white/yellow, imprinted with WATSON 410, 50 mg

Monodox 100 mg

brown/yellow, imprinted with MONODOX 100, M 259

Periostat

white, imprinted with TM Periostat, 20 mg

What are the possible side effects of doxycycline?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using doxycycline and call your doctor at once if you have any of these serious side effects:

• severe headache, dizziness, blurred vision;
• fever, chills, body aches, flu symptoms;
• severe blistering, peeling, and red skin rash;
• urinating less than usual or not at all;
• pale or yellowed skin, dark colored urine, fever, confusion or weakness;
• severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
• loss of appetite, jaundice (yellowing of the skin or eyes); or
• easy bruising or bleeding, unusual weakness.

Less serious side effects may include:

• swollen tongue, trouble swallowing;
• mild nausea, vomiting, diarrhea, or stomach upset;
• white patches or sores inside your mouth or on your lips;
• sores or swelling in your rectal or genital area; or
• vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about doxycycline?

Do not use this medication if you are pregnant. It could cause harm to the unborn baby, including permanent discoloration of the teeth later in life. Doxycycline can make birth control pills less effective. Use a second method of birth control while you are taking doxycycline to keep from getting pregnant.

Doxycycline passes into breast milk and may affect bone and tooth development in a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Do not use this medication if you are allergic to doxycycline, or to similar medicines such as demeclocycline (Declomycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

Before taking doxycycline, tell your doctor if you have liver or kidney disease. You may not be able to take doxycycline, or you may need a dose adjustment or special tests during treatment.

Do not give doxycycline to a child younger than 8 years old. Doxycycline can cause permanent yellowing or graying of the teeth, and it can affect a child's growth.

Throw away any unused doxycycline when it expires or when it is no longer needed. Do not take any doxycycline after the expiration date printed on the bottle. Expired doxycycline can cause a dangerous syndrome resulting in damage to the kidneys.

What should I discuss with my healthcare provider before taking doxycycline?

Do not use this medication if you are allergic to doxycycline, or to similar medicines such as demeclocycline (Declomycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

Before taking doxycycline, tell your doctor if you have liver or kidney disease. You may not be able to take doxycycline, or you may need a dose adjustment or special tests during treatment.

If you are using doxycycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.

Do not use doxycycline syrup (Vibramycin) without first talking to your doctor if you have asthma or are allergic to sulfites.

FDA pregnancy category D. This medication can cause harm to an unborn baby, including permanent discoloration of the teeth later in life. Do not use doxycycline without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Doxycycline can make birth control pills less effective. Use a non-hormonal method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while you are taking doxycycline.

Doxycycline passes into breast milk and may affect bone and tooth development in a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

Children younger than 8 years old should not take doxycycline. Doxycycline can cause permanent tooth discoloration and can also affect a child's growth.

How should I take doxycycline?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take doxycycline with a full glass of water (8 ounces).

You may take this medication with or without food. Do not take the medication with milk or other dairy products, unless your doctor has told you to. Dairy products can make it harder for your body to absorb the medicine. Certain brands of doxycycline may not have restrictions about taking them with dairy products. If your doctor has instructed you to take doxycycline with milk, tell your pharmacist that you need a brand of doxycycline that can be taken with milk.

Do not crush, break, or open a delayed-release capsule (Orecea). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Doxycycline will not treat a viral infection such as the common cold or flu. Do not give this medicine to another person, even if they have the same condition you have.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking doxycycline. You may need to stop using the medicine for a short time.

Throw away any unused doxycycline when it expires or when it is no longer needed. Do not take any doxycycline after the expiration date printed on the label. Using expired doxycycline can cause damage to your kidneys.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, and diarrhea.

What should I avoid while taking doxycycline?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Doxycycline can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking doxycycline.

What other drugs will affect doxycycline?

Before taking doxycycline, tell your doctor if you are taking any of the following drugs:

• cholesterol-lowering medications such as cholestyramine (Prevalite, Questran) or colestipol (Colestid);
• isotretinoin (Accutane);
• tretinoin (Renova, Retin-A, Vesanoid);
• an antacid such as Tums, Rolaids, Milk of Magnesia, Maalox, and others;
• a product that contains bismuth subsalicylate such as Pepto-Bismol;
• minerals such as iron, zinc, calcium, magnesium, and over-the-counter vitamin and mineral supplements;
• a blood thinner such as warfarin (Coumadin); or
• a penicillin antibiotic such as amoxicillin (Amoxil, Trimox, others), penicillin (BeePen-VK, Pen-Vee K, Veetids, others), dicloxacillin (Dynapen), carbenicillin (Geocillin), oxacillin (Bactocill), and others.

This list is not complete and there may be other drugs that can interact with doxycycline. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about doxycycline.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Last Updated: April 12, 2009